I. The Caſe of the Right Reverend the Lord Biſhop of BATH and WELLS.

ABOUT Five Years ago he felt a Soreneſs in his Left Side, after having rode Four Days together, and made Water, which was firſt coffee-colour'd, and then bloody. Theſe Complaints went off in a ſhort time; however, he became, after this, ſubject to make bloody Water upon Riding: He felt once a moſt violent Pain along the [2]Region of the Right Ureter; it laſted only for a Moment, and happened during a Fit of Cholic, occaſioned by eating Strawberries. About Two Years ago he was obliged to for⯑bear riding, and could hardly walk without making bloody Water; had Pain in making Water, and a Forcing to go to Stool at the ſame time, but no Stoppage: He began Mrs. Ste⯑phens's Medicines in April laſt; they increaſed the Pain in making Water for ſome time; his Water became turbid at the time of making, had ropy fetid Matter in it, depoſited a thick heavy Sediment, and many ſmall Flakes and Fragments of Stones were voided with it in a ſoft State: In Five or Six Weeks he grew much better, and was able to go over the Stones in his Coach: His general Health was alſo much improved. In the Beginning of July he had a Return of the Pain in making Water, with a ſudden Stoppage now and then: Upon this he voided ſeveral Pieces of Stone in a ſoft State, with one pretty large Piece, Part of which was ſoft and white, Part brown and hard, and it gave a little Pain in paſſing: After this the Pain and Stoppage in making Water went off intirely. In September he went into the Coun⯑try, where he often rides a trotting Horſe with⯑out any Inconvenience; and is free from all Complaints, excepting that he has now and then ſome uneaſy Senſations in the Region of the Kidneys: He has continued the Medicines till a little while ago; but his Water has been in general perfectly clear, during the Uſe of [3]them; whereas it has twice been turbid upon diſcontinuing them, and depoſits a red Sedi⯑ment, which dries into a ſtony Subſtance.

II. The Caſe of Mr. Binford, at Mr. Cameray's, in Tokenhouſe-yard, Throgmorton-ſtreet.

HE had a Stone taken out of his Bladder by the Operation, when about Ten Years old; has had the Symptoms of a Stone in the Blad⯑der now again, for about Six Years. A Sur⯑geon at Exeter examined him twice by the Finger in the Anus, and found both times in the moſt evident manner a Stone in the Blad⯑der, which he imagined to be as big as an Egg. Mr. Binford perceived the Motions of this Stone during the Examinations, and made bloody Water after one of them. He began Mrs. Stephens's Medicines about the middle of laſt Auguſt, and in a ſhort time after voided many white Scales, and much brown Grit in a ſoft and rotten State: Since this he has voided many irregular Shells of Stone, of a conſiderable Size, and of ſuch a Thickneſs, as to conſiſt of ſeveral Coats, from Two to Six in Number: [4]Many of theſe, when voided, are covered with a Whiteneſs, which being rubb'd off, the Shell appears to be brown. On the 30th of January he had a Suppreſſion of Urine; Mr. Hawkins paſſed the Catheter then, and found a Stone in the Bladder, which he told Mr. Binford he believed to be very ſmall, tho' he would not preſume to be certain. Mr. Binford has voided many more Pieces of Stone ſince this, and Mrs. Stephens is in daily Expectation of his being perfectly well.

III. The Caſe of Mr. Bolton, at the Sun and Dolphin in Cheapſide, contained in a Letter directed to me.

TOWARDS the latter Part of my Life, when in my Fiftieth Year, about 1720, I was ſore pained with the Stone, until I voided a large one; at ſeveral times ſince about a Dozen; Part came away after a little riding, and then I made Water like Coffee: But I imagine, one of the largeſt might ſtay behind; for in 1735 I began to be greatly afflicted; could not endure to ride, or bear a Coach: When I have been making Water, it often [5]ſtopped on a ſudden, cauſing much Pain; and no Perſon in the Country could give Relief, tho' I took a many odd Things. Reading the Papers, I obſerved, ſome Specificks for the Stone were advertized, one a Powder, the other a Liquid: I got 'em, and try'd each; but was not able to go thro' with either of 'em; being of a forcing Nature, increaſed my Pain: Then was adviſed to ſmooth palliating Medi⯑cines, yet Pain ſtill continued, and exceſſive; made me begin to think of coming up to Lon⯑don to be cut, if it might be ſafely done at my Age: At that time the News informed us, that the Biſhop of Bath and Wells and others were cured by taking Mrs. Stephens's Medi⯑cines: I was then more inclinable to come: When I ſet out, my Thoughts were to un⯑dergo the manual Operation, and had wrote to Mr. Cheſelden about it: When I arrived in London, and conſulted with ſome Friends, it was thought, as I was in my 68th Year, the ſafeſt way to take Mrs. Stephens's Medicines; and accordingly on the 18th of July, 1737, I began with 'em, taking Three Powders, and Three half Pints of Liquid every Day: What Effect, and how they did operate, you will ſee by the following Diary, which I kept as exactly as I could, conſidering the Pain I had by times; which yet prompted me to keep ſtrictly to the Medicines, believing, that by ſo doing, I ſhould the ſooner be made eaſy, and took the Liquid Four times a Day for ſome Weeks.

IV. The Caſe of the Honourable Mr. Carteret, Poſtmaſter General.

HAVING been very much afflicted with the Stone and Gravel, and having by the beſt means I could, endeavour'd to get Relief, at length, in the utmoſt of my Extremity, I was recommended to Mrs. Stephens; and ſoon [19]after taking her Medicines, I began to bring away in my Urine a whitiſh Powder, which, when dry, appeared to be what came from a Stone. This continued for ſome time, and in about Two or Three Months I found my⯑ſelf freed from a Pain, I had felt at times for ſeveral Years, on the Right Side of the Bladder. And I am well aſſured, it was a Stone or cal⯑culous Matter, which ſtuck to the Bladder. Beſides this, I had a looſe Stone in the Bladder, which for ſeveral Months after gave me ex⯑treme Pain, by its forcing when I made Wa⯑ter; which at length came away in Pieces, almoſt every time I made Water, for about Nine Weeks following; until at laſt it came all away, as appeared by my being freed from all manner of Pain. The Kernel of the Stone itſelf having come away, I thought myſelf then intirely well, tho' afterwards, upon a Journey to London, ſome Stones fell from my Kidneys, which came away to the Number of Seven at one time, which made me preſume too far in diſcontinuing the Medicines in great Part, having little or no Pain; when a Stone, which had ſtuck in the Ureters, came down, and ſtopped the Paſſage of the Urine, which occaſioned a Suppreſſion of it, and out of Fear of its not paſſing, I had the Aſſiſtance of Mr. Cheſelden; and, I thank God, I am now free of any Pain, and have been ſo ever ſince.

V. The Caſe of Mr. Daubuz, in Throg⯑morton-ſtreet.

HE has been ſubject to void Gravel for a long time, and had the following Com⯑plaints for about Ten Months. Pain along the Urethra, and at the Neck of the Bladder, eſpe⯑cially upon walking much, or going in a Coach. Violent Pain and Difficulty in make⯑ing Water: A ſudden Stoppage very often: Forcing to go to Stool: Bloody Water upon much Motion. He began Mrs. Stephens's Me⯑dicines the firſt Week of laſt Auguſt: Upon this his Water became turbid at the time of making, and he voided a good deal of red Gravel. He was much better in a Month, free from all Complaints in Six Weeks, and his Water ceaſed to be turbid at the time of making, tho' he ſtill continued the Uſe of the Medicines. He left them off in October, hav⯑ing voided Three ſmall Stones, Two flat, and One round, a little before this; and has been perfectly well ever ſince.

VI. The Caſe of Mr. Holland, Warder of the Tower.

HAS had Pains in the Region of the Kid⯑neys, with the voiding of ſmall Stones, ever ſince the Year 1721. In Auguſt 1734, had a very bad Fit, but voided no Stone after it. In the October following found, that he could neither bear a Coach, ride, nor walk, without a great deal of Pain, and often make⯑ing bloody Water. Had frequent Provocations to make Water, and made very little at a time. He began Mrs. Stephens's Medicines on the Third of laſt October: Upon this his Water became white, and had ſmall white Gravel in it, like Scrapings of Chalk. He was in great Pain for the firſt Month after he began the Medicines. November the Fourth he was examined by the Catheter, and a Stone was found in the Bladder. Since this he has voided ſeveral Scales like Egg-ſhells, white on one Side, and brown on the other, with many white rotten Bits of Stone. He is at preſent very eaſy, can walk very well, and continues the Uſe of the Medicines.

Witneſs my Hand to the Truth of this.

VII. The Caſe of Mr. Neau, in Compton⯑ſtreet, near St. Ann's Church.

HAS had the Symptoms of a Stone in the Bladder for about Six Years: Was exa⯑mined ſoon after the Appearance of theſe Symptoms by the Catheter, and a Stone found in the Bladder. Had great Pain and Difficulty in making Water; a ſudden Stoppage often; Forcings to go to Stool; And made bloody Water upon Motion. He began Mrs. Ste⯑phens's Medicines upon the Fifteenth of laſt September. He was examined by the Catheter on the Twenty-ſeventh of October, and a Stone was found in the Bladder. Upon taking the Medicines his Water became turbid at the time of making, and he has voided ſeveral white Shells in ſo ſoft a State, as to crumble eaſily, with one large irregular Stone. He voided a large Stone and ſeveral Shells before he took the Medicines, but they were all brown, and very hard. He has now very few Complaints, is able to go over the Stones in a Coach, with⯑out Inconvenience, and continues the Uſe of the Medicines.

VIII. The Caſe of Mr. Snape, in Panton-ſtreet, near the Hay-Market.

ABOUT Three Years ago he began to have a Pain in making Water, made little at a time, and had a Provocation to it every Quarter of an Hour. Had violent Force⯑ings to go to Stool at the ſame time: Made bloody Water upon much Motion. In the End of the Year 1735, after having taken ſome lenitive Electuary, he voided many ſmall Stones in a hard State, but received no Relief thereby. In April 1736 he began Mrs. Stephens's Medicines: Upon the Uſe of theſe he grew much eaſier, his Water became turbid at the time of making, and he voided a great Number of ſmall Stones in a ſoft State, which by their Corners ſeemed to have been Pieces of larger. He took the Medicines for about a Year, and has been perfectly well ever ſince he left them off.

IX. The Caſe of the Rev. Dr. Sykes, in Great Marlborough-ſtreet.

HE has been ſubject to Pains in his Back, with Vomitings, and the voiding of ſmall Stones, for many Years. About Four or Five Years ago, after a Jolt in a Coach, he had a Pain in making Water, which con⯑tinued about Three Weeks. In November 1736, after another Jolt, he had a Return of the ſame ſort of Pain in making Water: This became very violent after ſome time, was often attended with a ſudden Stoppage, and he had great Provocation to make Water, eſpecially upon Motion: Made bloody Water after much Motion in the Chariot; had an uneaſy Sen⯑ſation in the Region of the Bladder, upon turning in Bed, as if ſomething moved within him. Theſe Diſorders continued about Four⯑teen Months, at the End of which, viz. in February laſt, he began to take Mrs. Stephens's Medicines. They increaſed his Pain in make⯑ing Water very much for ſome Days; his Wa⯑ter depoſited a white heavy Sediment, and he voided many Flakes of Stone in a ſoft State, and ſome Fragments in a hard one. He grew eaſy and free from all Complaints in about Two Months, excepting that he had now and [25]then ſome ſmall Pains in the Region of the Ureters. However, he continued the Uſe of the Medicines till the End of Auguſt, his Wa⯑ter depoſiting a white heavy Sediment, till the laſt Ten Days or Fortnight of taking. He has continued perfectly well ever ſince, and can ride a trotting Horſe, or go over the Stones in a Coach, without any Inconvenience.

X. The Caſe of Mr. Thomas.

HE had the uſual Symptoms of a Stone in the Bladder, and began Mrs. Stephens's Medicines in September laſt, being about 75 Years old. October the Eighth Mr. Hawkins examined him, and found a Stone in the Blad⯑der, which he told Mr. Thomas, he believed to be a large one: Upon firſt taking the Me⯑dicines Mr. Thomas's Water depoſited much heavy Sediment, which dried into a ſtony Subſtance: Some time after he voided ſoft white Scales in great Quantities with Grit and Slime, which I ſaw. His Pains were great at this time: They continued, he loſt his Appe⯑tite, grew feveriſh, and died Jan. 20. His Body was opened, and a Stone taken out of the Bladder. This Stone Dr. Shaw and Mr. Hawkins ſaw Jan. 30. I ſaw Dr. Shaw that Evening, and took down from his Mouth the [26]following Words, relating to the Appearance of the Stone.

The next Day I ſaw Mr. Hawkins, and took down from his Mouth the following Words relating to the Appearance of the Stone: ‘He ſaw a Stone weighing nearly Two Ounces, as Mrs. Thomas ſaid. The Surface was of a whitiſh Colour, and in Part covered with a Matter that had all the Appearance of the ſoft Shells that had before come away in Mr. Thomas's Water. This Matter was very ſoft, and ready to fall off and crumble upon the leaſt Touch. By theſe Appearances he ſays, that he ſhould imagine that the Stone had been larger, and that this ſoft Matter ſeem'd to he ready to fall off in a little time. The [27]Part of the Stone not covered with this ſcaly Matter, appeared, when ſcraped with a Knife, of a ruſty Iron Colour, and conſiderably hard.’

ANY Perſon who is diſpoſed to inquire more particularly into the Effects of theſe Medi⯑cines, may have a Liſt of thoſe that take them, at Mr. Winter's, in Richbell-Court, Red-Lyon-ſtreet, from whence they are given out: However, I hope, theſe Ten Caſes will be ſuffi⯑cient to engage the Attention of all Well-Wiſhers to Mankind; and I have been determined in my Choice of them, rather by the Eminence of the Perſons, by their living in Town, or by the ſtrong Preſumption of at leaſt a partial Diſſo⯑lution of a Stone, than by the Greatneſs of the Benefit received. Some of theſe are indeed complete Cures, as far as one can judge; but there are ſeveral others as complete among Per⯑ſons of leſs Note, or who live at a Diſtance from London; and that, with all the probable Cir⯑cumſtances of the gradual waſting and crum⯑bling of Stones. There are alſo a great Number of unfiniſhed Caſes, which add much Light and Evidence to theſe Ten. Neither are theſe Medi⯑cines prejudicial to the Body; but, on the con⯑trary, have plainly improved the general Health of many, that have taken them. I ſtill go on with my Inquiries in the moſt impartial manner I can; and ſhould be extremely ſorry, not only to deceive myſelf, but to be any Occaſion of im⯑poſing upon others.